state that all viruses are non-cellular structures with a nucleic acid core (either DNA or RNA) and a capsid made of protein, and that some viruses have an outer envelope made of phospholipids

Published by Patrick Mutisya · 14 days ago

Cambridge A-Level Biology – Cells as the Basic Units of Living Organisms

Cells as the Basic Units of Living Organisms

Learning Objective

State that all viruses are non‑cellular structures with a nucleic acid core (either DNA or RNA) and a capsid made of protein, and that some viruses have an outer envelope made of phospholipids.

Key Points

  • Viruses are not cells; they lack the machinery required for independent metabolism and reproduction.
  • Every virus contains a nucleic acid genome:

    • DNA viruses – double‑stranded or single‑stranded DNA.
    • RNA viruses – double‑stranded, single‑stranded positive‑sense (+) RNA, or single‑stranded negative‑sense (–) RNA.

  • The genome is enclosed within a protein shell called a capsid. The capsid is composed of repeating protein subunits called capsomeres.
  • Some viruses possess an additional outer layer called an envelope, which is derived from the host cell’s phospholipid membrane and contains viral glycoproteins.

Structural Summary of a Typical \cdot irus

ComponentDescriptionPresence in \cdot iruses
Nucleic Acid CoreDNA or RNA, may be single or double strandedAll viruses
CapsidProtein shell made of capsomeres; determines shape (icosahedral, helical, complex)All viruses
EnvelopePhospholipid bilayer derived from host membrane; contains viral glycoproteins for attachmentOnly enveloped viruses (e.g., influenza, HIV)

Why \cdot iruses Are Considered Non‑Cellular

  1. They lack a cytoplasm and organelles.
  2. They cannot carry out metabolic reactions on their own.
  3. Replication occurs only inside a host cell, using the host’s biosynthetic machinery.

Comparison: Cells vs. Viruses

FeatureCellVirus
MembranePlasma membrane (phospholipid bilayer)May have envelope (phospholipid) or none
Genetic MaterialDNA (usually double‑stranded) in nucleusDNA or RNA, single or double stranded
MetabolismSelf‑contained metabolic pathwaysNone; depends on host
ReproductionCell division (mitosis/meiosis)Assembly within host cell after replication of genome
SizeTypically 1–100 µm20–300 nm

Suggested diagram: Schematic of a non‑enveloped virus (capsid only) and an enveloped virus (capsid + phospholipid envelope) showing the nucleic acid core, capsid proteins, and envelope glycoproteins.