state that all viruses are non-cellular structures with a nucleic acid core (either DNA or RNA) and a capsid made of protein, and that some viruses have an outer envelope made of phospholipids
Cambridge A-Level Biology – Cells as the Basic Units of Living Organisms
Cells as the Basic Units of Living Organisms
Learning Objective
State that all viruses are non‑cellular structures with a nucleic acid core (either DNA or RNA) and a capsid made of protein, and that some viruses have an outer envelope made of phospholipids.
Key Points
Viruses are not cells; they lack the machinery required for independent metabolism and reproduction.
Every virus contains a nucleic acid genome:
DNA viruses – double‑stranded or single‑stranded DNA.
The genome is enclosed within a protein shell called a capsid. The capsid is composed of repeating protein subunits called capsomeres.
Some viruses possess an additional outer layer called an envelope, which is derived from the host cell’s phospholipid membrane and contains viral glycoproteins.
Structural Summary of a Typical \cdot irus
Component
Description
Presence in \cdot iruses
Nucleic Acid Core
DNA or RNA, may be single or double stranded
All viruses
Capsid
Protein shell made of capsomeres; determines shape (icosahedral, helical, complex)
All viruses
Envelope
Phospholipid bilayer derived from host membrane; contains viral glycoproteins for attachment
Only enveloped viruses (e.g., influenza, HIV)
Why \cdot iruses Are Considered Non‑Cellular
They lack a cytoplasm and organelles.
They cannot carry out metabolic reactions on their own.
Replication occurs only inside a host cell, using the host’s biosynthetic machinery.
Comparison: Cells vs. Viruses
Feature
Cell
Virus
Membrane
Plasma membrane (phospholipid bilayer)
May have envelope (phospholipid) or none
Genetic Material
DNA (usually double‑stranded) in nucleus
DNA or RNA, single or double stranded
Metabolism
Self‑contained metabolic pathways
None; depends on host
Reproduction
Cell division (mitosis/meiosis)
Assembly within host cell after replication of genome
Size
Typically 1–100 µm
20–300 nm
Suggested diagram: Schematic of a non‑enveloped virus (capsid only) and an enveloped virus (capsid + phospholipid envelope) showing the nucleic acid core, capsid proteins, and envelope glycoproteins.