Published by Patrick Mutisya · 14 days ago
Outline the role of sensory receptor cells in detecting stimuli and stimulating the transmission of impulses in sensory neurones.
Sensory receptor cells are specialised cells that convert a specific type of environmental stimulus into an electrical signal (a receptor potential). This process is called sensory transduction.
Although the morphology varies, most receptor cells share these features:
When a stimulus acts on the receptor cell, it causes a change in the permeability of the cell membrane to specific ions. This generates a graded change in membrane potential called the receptor potential.
The magnitude of the receptor potential is proportional to the intensity of the stimulus.
Key steps:
Pressure on the skin deforms Meissner’s corpuscles → stretch‑sensitive channels open → receptor potential → action potential in the associated dorsal root ganglion neurone → dorsal column‑medial lemniscal pathway.
Photons are absorbed by retinal pigments in rods/cones → conformational change in opsin → closure of Na⁺ channels → hyperpolarisation (inverse of most receptors) → modulation of glutamate release → signal transmitted via bipolar cells to optic nerve.
Soluble chemicals bind to G‑protein‑coupled receptors on taste buds → second‑messenger cascade → opening of ion channels → depolarisation → action potential in gustatory neurones → cranial nerves \cdot II, IX, X.
| Receptor Type | Stimulus Detected | Primary Ion(s) Involved | Typical Location | Pathway to CNS |
|---|---|---|---|---|
| Mechanoreceptor (e.g., Pacinian corpuscle) | Vibration, deep pressure | Na⁺, Ca²⁺ | Dermis, subcutaneous tissue | Dorsal column‑medial lemniscal system |
| Thermoreceptor (cold) | Decrease in temperature | K⁺ (outward), Na⁺ (inward) | Skin, hypothalamus | Spinothalamic tract |
| Photoreceptor (rod) | Low‑intensity light | Na⁺ (closed), Ca²⁺ (closed) | Retina | Optic nerve → thalamus → visual cortex |
| Chemoreceptor (olfactory) | Odour molecules | Na⁺, Ca²⁺ (via second messenger) | Olfactory epithelium | Olfactory nerve → olfactory bulb → cortex |
| Nociceptor | Potentially damaging mechanical, thermal, chemical stimuli | Na⁺, Ca²⁺ | Skin, muscles, viscera | Spinothalamic tract |