explain that genetic engineering may help to solve the global demand for food by improving the quality and productivity of farmed animals and crop plants, using the examples of GM salmon, herbicide resistance in soybean and insect resistance in cotto

Published by Patrick Mutisya · 8 days ago

Cambridge A-Level Biology 9700 – Genetically Modified Organisms in Agriculture

Genetically Modified Organisms (GMOs) in Agriculture

Learning Objective

Explain how genetic engineering can help meet the global demand for food by improving the quality and productivity of farmed animals and crop plants, using the examples of GM salmon, herbicide‑resistant soybean and insect‑resistant cotton.

Why Food Production Needs Innovation

  • World population projected to exceed 9 billion by 2050.
  • Limited arable land and increasing pressure on natural resources.
  • Climate change introduces new stresses (drought, pests, disease).
  • Traditional breeding is time‑consuming; genetic engineering offers precise, rapid solutions.

Key Concepts of Genetic Engineering

  1. Identification of a desirable trait (e.g., faster growth, herbicide tolerance).
  2. Isolation of the gene(s) responsible for that trait.
  3. Insertion of the gene into the target organism’s genome using vectors (plasmids, Agrobacterium, microinjection).
  4. Selection of successfully transformed individuals and propagation.
  5. Regulatory assessment for safety, environmental impact and labeling.

Case Studies

1. GM Salmon (AquAdvantage®)

The AquAdvantage salmon contains a growth hormone gene from the Chinook salmon linked to a promoter from the ocean pout, allowing continuous production of growth hormone.

Result:

  • Reaches market size in ≈ 18 months instead of 30–36 months.
  • Feed conversion ratio improves by about 25 %.
  • Potential to reduce pressure on wild fish stocks.

Suggested diagram: Gene construct used in AquAdvantage salmon showing the growth‑hormone gene and promoter.

2. Herbicide‑Resistant Soybean (e.g., Roundup Ready®)

These soybeans carry a gene encoding a modified 5‑enolpyruvylshikimate‑3‑phosphate synthase (EPSPS) enzyme that is insensitive to glyphosate.

Benefits:

  • Farmers can apply glyphosate to control weeds without harming the crop.
  • Reduces the need for mechanical tillage, conserving soil structure and moisture.
  • Allows earlier planting and multiple cropping cycles in some regions.

Suggested diagram: Mode of action of glyphosate and how the modified EPSPS confers resistance.

3. Insect‑Resistant Cotton (Bt Cotton)

Bt cotton expresses a toxin (Cry protein) derived from the bacterium Bacillus thuringiensis that is lethal to specific lepidopteran pests.

Outcomes:

  • Reduces pesticide applications by up to 70 %.
  • Increases yield stability in pest‑prone areas.
  • Economic savings for farmers and lower environmental pesticide load.

Suggested diagram: Cry protein expression in cotton cells and its effect on insect gut lining.

Comparative Overview

TraitOrganismIntroduced Gene(s)Primary BenefitPotential Environmental/Ethical Considerations
Accelerated growthAtlantic salmonGrowth‑hormone gene (Chinook) + ocean‑pout promoterFaster market size, lower feed useContainment of escaped GM fish; impact on wild gene pool
Herbicide toleranceSoybeanModified EPSPS enzyme (glyphosate‑resistant)Simplified weed management, reduced tillageHerbicide over‑use; emergence of resistant weeds
Insect resistanceCottonCry1Ac toxin (Bt)Lower pesticide use, higher yieldsPotential resistance development in target insects

Linking GMOs to Global Food Security

Mathematically, the additional production from GM crops can be expressed as:

\$\Delta P = P{\text{GM}} - P{\text{conventional}} = A \times Y{\text{GM}} - A \times Y{\text{conv}}\$

where \$A\$ is the cultivated area and \$Y\$ is yield per unit area. If GM technology raises yield by 15 % (\$Y{\text{GM}} = 1.15Y{\text{conv}}\$), the increase in production \$\Delta P\$ can be substantial even without expanding farmland.

Critical Evaluation Points for Students

  • Assess the trade‑offs between increased productivity and ecological risks.
  • Consider socioeconomic impacts: farmer dependence on patented seeds, market access.
  • Discuss regulatory frameworks and public perception.
  • Explore alternative technologies (e.g., CRISPR, marker‑assisted selection) and their comparative advantages.

Summary

Genetic engineering offers powerful tools to enhance the quantity and quality of food production. The three case studies illustrate how specific traits—faster growth in animals, herbicide tolerance, and insect resistance in crops—can directly address challenges of a growing population, limited resources, and environmental sustainability. Critical appraisal of benefits, risks, and ethical considerations remains essential for responsible deployment of GMOs in agriculture.