Lesson Plan

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Lesson Plan
Grade: Date: 17/01/2026
Subject: Biology
Lesson Topic: outline the role of stem cells in cell replacement and tissue repair by mitosis
Learning Objective/s:
  • Describe the two fundamental properties of stem cells (self‑renewal and potency).
  • Explain how stem cells contribute to cell replacement and tissue repair through mitosis.
  • Identify the stages of mitosis and their relevance to stem‑cell‑mediated regeneration.
  • Analyse the regulatory signals that control stem‑cell proliferation.
  • Evaluate clinical applications of stem‑cell‑driven mitosis.
Materials Needed:
  • Projector and screen
  • PowerPoint slides with stem‑cell and mitosis diagrams
  • Printed worksheet with stem‑cell case studies
  • Whiteboard and markers
  • Microscopy images of tissue samples (optional)
  • Exit‑ticket cards
 Introduction:
Begin with a short video clip showing skin healing after a cut to spark curiosity. Ask students what cellular processes might enable such rapid repair, linking to prior knowledge of cell division. Clarify that today they will explore how stem cells drive tissue replacement via mitosis and outline the success criteria: define stem‑cell properties, trace the mitotic sequence, and discuss regulation.
Lesson Structure:
  1. Do‑now (5') – Quick quiz on cell‑cycle phases displayed on the board.
  2. Mini‑lecture (10') – Introduce stem‑cell properties and types with slides.
  3. Interactive table activity (10') – Students complete a comparison chart of ESCs, adult stem cells, and iPSCs.
  4. Demonstration (8') – Animated walk‑through of mitosis stages, linking each stage to stem‑cell‑mediated repair.
  5. Group case study (12') – Analyse a tissue (e.g., blood) and map stem‑cell division to cell replacement.
  6. Regulation discussion (8') – Whole‑class discussion of growth factors, checkpoints, and niche signals.
  7. Formative check (5') – Exit ticket: one sentence describing how mitosis enables tissue repair.
Conclusion:
Summarise that stem cells maintain tissue integrity by self‑renewing and differentiating through precisely timed mitotic divisions, and highlight the key regulatory cues that ensure safe proliferation. Collect exit tickets and assign a brief homework: write a paragraph linking a chosen clinical application (e.g., regenerative medicine) to the mitotic process discussed.