| Lesson Plan |
| Grade: |
Date: 25/02/2026 |
| Subject: Biology |
| Lesson Topic: state that enzymes are globular proteins that catalyse reactions inside cells (intracellular enzymes) or are secreted to catalyse reactions outside cells (extracellular enzymes) |
Learning Objective/s:
- Describe the structural nature of enzymes as globular proteins.
- Explain the difference between intracellular and extracellular enzymes and give examples.
- Illustrate how enzymes lower activation energy and facilitate biochemical reactions.
- Analyze the main factors that influence enzyme activity (temperature, pH, substrate concentration, inhibitors, cofactors).
- Compare the regulation mechanisms of intracellular versus extracellular enzymes.
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Materials Needed:
- Projector and screen
- PowerPoint slides with diagrams
- Handouts summarising key points and the comparison table
- Whiteboard and markers
- Sample enzyme models or 3‑D printed protein models (optional)
- Worksheets with practice questions
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Introduction:
Begin with a quick “What enzyme do you use every day?” brainstorm to activate prior knowledge. Highlight that enzymes are specialised proteins that speed up reactions inside or outside cells. State that by the end of the lesson students will be able to identify and compare intracellular and extracellular enzymes and explain how they work.
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Lesson Structure:
- Do‑now (5’) – Students list familiar enzymes and classify them as intracellular or extracellular.
- Mini‑lecture (10’) – Define enzymes as globular proteins, explain catalysis and activation‑energy reduction using slides.
- Comparative activity (10’) – In pairs, complete a Venn diagram contrasting intracellular vs extracellular enzymes with examples.
- Mechanism demonstration (10’) – Show an animation of the enzyme‑substrate complex and discuss transition‑state stabilization.
- Factors investigation (10’) – Small groups analyse case scenarios (temperature, pH, inhibitors, cofactors) and predict effects on reaction rates.
- Formative quiz (5’) – Kahoot/exit‑ticket with three questions covering all objectives.
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Conclusion:
Recap the key differences between intracellular and extracellular enzymes and the ways they lower activation energy. Ask students to write one “exit ticket” statement summarising a factor that influences enzyme activity and assign a short worksheet for homework to reinforce the concepts.
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