| Lesson Plan |
| Grade: |
Date: 25/02/2026 |
| Subject: Biology |
| Lesson Topic: outline glycolysis as phosphorylation of glucose and the subsequent splitting of fructose 1,6-bisphosphate (6C) into two triose phosphate molecules (3C), which are then further oxidised to pyruvate (3C), with the production of ATP and reduced NAD |
Learning Objective/s:
- Describe the two ATP‑investment steps that convert glucose to fructose‑1,6‑bisphosphate.
- Explain how aldolase and triose phosphate isomerase split and interconvert the 3‑carbon products.
- Illustrate the oxidation of each triose phosphate to pyruvate, including NADH and ATP generation.
- Calculate the net ATP and NADH yield from one molecule of glucose.
- Interpret a glycolysis pathway diagram to identify key enzymes and intermediates.
|
Materials Needed:
- Projector or interactive whiteboard
- PowerPoint/Google Slides of glycolysis pathway
- Student worksheet with blank pathway diagram
- Molecular model kits (optional)
- Exit‑ticket slips
|
Introduction:
Begin with a quick video clip showing how cells harvest energy from sugar, then ask students to recall what they know about ATP investment. Explain that today they will trace glucose’s journey through glycolysis and identify where energy is captured.
|
Lesson Structure:
- Do‑Now (5’): Students list the three stages of glycolysis on a sticky note.
- Direct Instruction (10’): Teacher presents the phosphorylation/investment phase using slides and highlights hexokinase and PFK‑1.
- Guided Practice (12’): Whole‑class walkthrough of the cleavage step; students label enzymes on a projected diagram.
- Collaborative Activity (15’): Small groups complete a worksheet that maps the payoff phase, filling in ATP and NADH production.
- Check for Understanding (5’): Quick “thumbs up/down” quiz on net yields.
- Think‑Pair‑Share (8’): Students explain why glycolysis occurs anaerobically in muscle cells.
- Wrap‑Up (5’): Review key enzymes and summarize the overall equation.
|
Conclusion:
Recap the flow of carbon and energy through glycolysis, emphasizing the net gain of 2 ATP and 2 NADH. Students complete an exit ticket stating one fact they learned and one question they still have. For homework, assign a short reflection on how glycolysis links to cellular respiration.
|